Screening/Prevention
Fruits and Vegetables Reduce Risk of Stomach Cancer
(02/01/2008)
According to an article recently published in the American Journal of Epidemiology, diets higher in vegetables and fruits and lower in foods common in Western diets (such as processed meats, soft drinks, and sugars) can significantly reduce the risk of developing stomach cancer.
Epstein-Barr Virus Not Associated with Gastric Cancer
(11/29/2007)
According to an article recently published in the British Journal of Cancer, individuals infected with the Epstein-Barr virus (EBV) do not have an increased risk of gastric cancer.
Incidence of Precancerous Changes to the Stomach is Declining
(08/21/2007)
According to the results of a study conducted in the Netherlands and published in the journal Gut, the frequency of precancerous changes to the stomach (atrophic gastritis, intestinal metaplasia, and dysplasia) is declining; this should result in a drop in stomach cancer rates in the future.
Airborne Exposure to Some Chemicals May Increase Stomach Cancer Risk
(03/14/2007)
According to an article recently published in the International Journal of Cancer, airborne exposure to some occupational carcinogens appears to increase the risk of noncardia gastric cancer among men.
No Beneficial Effect of Vitamin Supplementation on Precancerous Changes to the Stomach
(01/17/2007)
According to the results of a clinical trial conducted in Venezuela, supplementation with vitamin C, vitamin E, and beta-carotene does not significantly affect the progression or regression of precancerous changes to the stomach. These results were published in the Journal of the National Cancer Institute.
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Stages I-II
Combination of Chemotherapy and Immunotherapy Shows Promise for Gastric Cancer
(03/24/2008)
A combination of chemotherapy and immunotherapy (chemoimmunotherapy) may improve overall survival among gastric cancer patients. These findings were recently published in the Annals of Oncology.
Identification of Cellular Enzymes May Predict Prognosis of Gastric Cancer
(02/27/2008)
An important enzyme known as histone deacetylase may contain useful information about the prognosis of gastric cancer. These findings were recently published in the Lancet.
S-1 Chemotherapy Following Surgery Improves Survival in Gastric Cancer
(11/07/2007)
According to an article recently published in the New England Journal of Medicine, treatment with the chemotherapy agent S-1 following surgery for Stages II-III gastric cancer improves survival compared with surgery alone with acceptable side effects.
PET Imaging May Help Guide Treatment of Esophageal and Gastric Cancers
(09/21/2007)
According to the results of a study published in Lancet Oncology, use of positron emission tomography (PET) imaging to evaluate response to neoadjuvant (before surgery) chemotherapy may help guide treatment of patients with cancer of the lower part of the esophagus or the upper part of the stomach (adenocarcinoma of the esophagogastric junction).
More Chemotherapy Not Beneficial in Gastric Cancer
(04/23/2007)
According to an article recently published in the Journal of the National Cancer Institute, intensive weekly chemotherapy with the regimen referred to as PELFw provides no benefit over the standard chemotherapy regimen consisting of 5FU/LV for treatment of patients with gastric cancer that is confined to the stomach or has spread to local lymph nodes.
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Stages III-IV
No Treatment Advantage with Cisplatin for Gastric Cancer
(04/02/2008)
Results from a recent study indicate that the addition of the drug cisplatin (Platinol®) did not improve response rates, survival rates, or progression-free survival for patients with gatric cancer. These findings were published in The Annals of Oncology.
Combination Chemotherapy Has Potential as Standard Treatment for Advanced Gastric Cancer
(03/03/2008)
A combination of S-1 and cisplatin chemotherapy may become the first-line therapy for patients with advanced gastric cancer. These findings were recently published in Lancet Oncology.
Identification of Cellular Enzymes May Predict Prognosis of Gastric Cancer
(02/27/2008)
An important enzyme known as histone deacetylase may contain useful information about the prognosis of gastric cancer. These findings were recently published in the Lancet.
Xeloda® and Eloxatin® Evaluated in Esophageal and Gastric Cancers
(01/04/2008)
According to the results of a Phase III clinical trial published in the New England Journal of Medicine, it may be possible to replace 5-FU (5-fluorouracil) with Xeloda® (capecitabine) and to replace cisplatin (Platinol®) with Eloxatin® (oxaliplatin) in the treatment of advanced esophageal and gastric cancers.
S-1 Chemotherapy Following Surgery Improves Survival in Gastric Cancer
(11/07/2007)
According to an article recently published in the New England Journal of Medicine, treatment with the chemotherapy agent S-1 following surgery for Stages II-III gastric cancer improves survival compared with surgery alone with acceptable side effects.
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Recurrent
Increased Doses of Gleevec® for Gleevec-Resistant Gastrointestinal Stromal Tumors (GIST) Effective
(08/17/2005)
According to a recent article published in the European Journal of Cancer, increasing doses of Gleevec® (imatinib) provides anti-cancer activity in patients diagnosed with Gastrointestinal Stromal Tumors (GIST) that had stopped responding to lower doses of the drug.
Lab Test Shows Promise for Detecting Gastric Cancer Recurrence
(02/08/2005)
A recent study in the American Journal of Clinical Oncology reports that a lab test analyzing a cancer marker known as carcinoembryonic antigen (CEA) may be useful in identifying patients who may be at risk for recurrence of gastric cancer.
Mortality from Some Cancer Surgeries Reduced in Large-Volume Hospitals
(01/23/2003)
According to a recent article published in
The New England Journal of Medicine, death related to surgical procedures (surgical mortality) for some cancers may be significantly reduced if patients receive treatment in hospitals that perform large volumes of the surgical procedure annually.
Postoperative Enteral Nutrition Reduces Complications in Gastrointestinal Cancer
(02/12/2002)
According to results published in the Lancet, postoperative enteral nutrition may significantly reduce complications and the length of hospital stays for patients with gastrointestinal cancer.